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Filtered Search Results
Medchemexpress LLC Chloroacetamido-C4-N 250mg
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Chloroacetamido-C4-NHBoc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC 6H-thieno[3,2-f]triazolo[4,3-a]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[6-[[[2-(2 ,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]methyl]amino]-6-oxohexyl]-2,3,9- trimethyl | 1957234-97-7 | 99.4% | 783.29 | 100 MG
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PROTAC BET Degrader-10 (dBET37) is a potent degrader of the BET protein BRD4, featuring a connection between ligands for Cereblon and BRD4, with a DC50 of 49 nM. The composition includes a BRD4(BD1BD2) ligand, a Cereblon ligand, and a linker. This product is intended for research use only.
- It is a potent BET protein BRD4 degrader.
- It is connected by ligands for Cereblon and BRD4.
- It has a DC50 of 49 nM.
- Purity is 99.39%.
- It is available in solid form.
- The color is off-white to light yellow.
- It can be shipped at room temperature in the continental US.
- Powder storage conditions are -20°C for 3 years or 4°C for 2 years.
- In solvent, storage conditions are -80°C for 6 months or -20°C for 1 month.
- It is soluble in DMSO at 100 mg/mL (127.67 mM).
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Medchemexpress LLC HY-18252 100mg Medchemexpress, Avanafil TA1790 CAS:330784-47-9 Purity:98%
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Medchemexpress,HY-18252 100mg Avanafil TA1790 CAS:330784-47-9 Formula:C23H26ClN7O3 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC CERDULATINIB HYDROC 50 mg
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CERDULATINIB HYDROC 50MG
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Medchemexpress LLC HY-101563 10mg Medchemexpress, GSK3326595 CAS:1616392-22-3 Purity:>98%
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Medchemexpress, HY-101563 10mg GSK3326595 CAS:1616392-22-3 GSK3326595 (EPZ015938) is a potent, selective, reversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 6.2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-103633 10mg Medchemexpress, PROTAC BET Degrader-1 CAS:2093386-22-0 Purity:>98%
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Medchemexpress, HY-103633 10mg PROTAC BET Degrader-1 CAS:2093386-22-0 PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreasing BRD2, BRD3, and BRD4 protein levels at low concentration. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10993 100mg , MK-1775 AZD1775;Adavosertib CAS:955365-80-7 Purity:98%
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Medchemexpress, HY-10993 100mg MK-1775 AZD1775;Adavosertib CAS:955365-80-7 Formula:C27H32N8O2 IC50: 5.2 nM (Wee1) Purity:98% MK-1775 is a potent Wee1 inhibitor with IC 50 of 5.2 nM. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 2093388-33-9 | Medchem Express | PROTAC BET degrader-2 | 5mg | 441681950 | HY-114228 | 770.851 | C41H42N10O6
Ambeed | 4-(2-Chloro-9H-purin-6-yl)morpholine | 250mg | 627733801 | A679575 | 4010-81-5 | MFCD17430374 | 239.660 | C9H10ClN5O
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eMolecules 1616392-22-3 | GSK3326595 | MFCD29991177 | 100mg
Ambeed | (4S4S)-22-(13-Bis(4-(adamantan-1-yl)phenyl)propane-22-diyl)bis(4-phenyl-45-dihydrooxazole) | 250mg | 696731481 | A1501025 | 2248620-13-3 | 755.059 | C53H58N2O2
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Medchemexpress LLC HY-112429 10mg Medchemexpress, HJB97 CAS:2093391-24-1 Purity:>98%
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Medchemexpress, HY-112429 10mg HJB97 CAS:2093391-24-1 HJB97 is a high-affinity BET inhibitor with Kis of 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), 1.0 nM (BRD4 BD2), respectively. HJB97 is employed for the design of potential PROTAC BET degrader and has antitumor activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 6H-Thieno[3,2-f]triazolo[4,3-a]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[6-[[[2-(2,6-dioxo | 1957234-97-7 | 99.4% | 783.29 | 10 MG
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PROTAC BET Degrader-10 (dBET37) is a potent BET protein BRD4 degrader, connected by ligands for Cereblon and BRD4, with a DC50 of 49 nM. This compound contains two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
- Potent BET protein BRD4 degrader
- Utilizes the intracellular ubiquitin-proteasome system for selective degradation
- Useful for research applications
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Medchemexpress LLC HY-19763 5mg Medchemexpress, BEBT-908 CAS:1235449-52-1 Purity:>98%
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Medchemexpress, HY-19763 5mg BEBT-908 CAS:1235449-52-1 BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor extracted from patent US/20120088764A1, Compound 243, has an IC50<0.1 μM, PI3Kα inhibitor 1 also inhibits HDAC (0.1 μM≤IC50≤1 μM) . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 1109276-89-2 | Medchem Express | PF-04620110 | 5mg | 446262211 | HY-13009 | MFCD19443642 | 396.447 | C21H24N4O4
Ambeed | tert-Butyl N-2-[2-(methylamino)ethoxy]ethylcarbamate | 1g | 650570796 | A865968 | 1185772-28-4 | MFCD25368799 | 218.297 | C10H22N2O3
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Medchemexpress LLC Cerdulatinib hydrochloride | 1369761-01-2 | MFCD28348366 | 99.0% | 482.00 g·mol⁻¹ | C20H28ClN7O3S | 10 MG
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Cerdulatinib hydrochloride is a selective, orally active, reversible ATP-competitive inhibitor of spleen tyrosine kinase (SYK) and Janus kinases (JAKs). It is used as a research compound for studies of immune signaling, autoimmune disease models, and B-cell malignancies.
- Selective dual SYK and JAK inhibition suitable for signaling studies.
- High reported purity appropriate for biochemical and cellular assays.
- Available in small solid quantities for preclinical research use.
- Soluble in DMSO, enabling preparation of concentrated assay stocks.
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Medchemexpress LLC HY-13522 50mg Medchemexpress, CUDC-907 fimepinostat CAS:1339928-25-4 Purity:98%
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Medchemexpress,HY-13522 50mg CUDC-907 fimepinostat CAS:1339928-25-4 Formula:C23H24N8O4S CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with IC50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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